A multimeric MR-optical contrast agent for multimodal imaging.
نویسندگان
چکیده
We describe the design, synthesis and in vitro evaluation of a multimodal and multimeric contrast agent. The agent consists of three macrocyclic Gd(III) chelates conjugated to a fluorophore and possesses high relaxivity, water solubility, and is nontoxic. The modular synthesis is amenable for the incorporation of a variety of fluorophores to generate molecular constructs for a number of applications.
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ورودعنوان ژورنال:
- Chemical communications
دوره 50 78 شماره
صفحات -
تاریخ انتشار 2014